pubmed📅 Source: October 07, 2026

Hellenia speciosa and liver protection in diabetics: what a study in rats reveals

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Affected srotas

udakavaha

Dhatus

raktavaha

Herbs in this article

Summary

Researchers demonstrated that the aqueous extract of the rhizome of Hellenia speciosa reduces hepatic lesions in diabetic rats induced by a high-fat diet and streptozotocin. The study, conducted by Filfilan and Elbeeh, observed that the administration of the extract led to a significant decrease in markers of liver damage, such as ALT and AST, which are enzymes indicative of liver injury. Additionally, an improvement in liver function and glycemic homeostasis was noted, suggesting that Hellenia speciosa may have a protective role against oxidative stress and hepatic inflammation. The authors highlight that, although the results are promising, the study was conducted in an animal model, which limits the generalization of the findings to humans. The relationship between the active principles of the plant and the mechanisms of hepatic protection still requires further investigation.

Key points

  • The extract of Hellenia speciosa reduced ALT and AST levels in diabetic rats.
  • The administration of the extract improved liver function and glycemic homeostasis.
  • The study was conducted in an animal model, limiting the extrapolation of the results to humans.
  • The mechanisms of hepatic protection still need to be elucidated.
  • The high-fat diet and streptozotocin were used to induce diabetes in the rats.

✦ For you

If you are concerned about your liver health, consider including foods that promote liver health in your diet, such as leafy vegetables and fruits rich in antioxidants. Additionally, pay attention to how your body reacts to different foods and lifestyles. If you notice persistent symptoms, seek a qualified health professional.

For practitionersExpand

Consider including Hellenia speciosa in formulas for patients with liver problems, especially those with type 2 diabetes. Assess liver function and treatment response, observing interactions with other herbs and medications. Research suggests a protective potential, but more studies are needed to confirm its clinical efficacy.

Reference

WM, Filfilan; ME, Elbeeh. Aqueous Hellenia speciosa rhizome extract attenuates hepatic injury in high-fat diet/streptozotocin-induced diabetic rats. PubMed (NLM E-utilities), 7 out. 2026. Disponível em: https://pubmed.ncbi.nlm.nih.gov/42843670/. Acesso em: 5 nov. 2026.

Curated by Lucas Campos · Ayurvedese®

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This content is informational and educational. It does not replace individual medical or therapeutic advice. See the terms of use.

Hellenia speciosa and liver protection in diabetics: what a study in rats reveals · Ayurvedese® Feed