Ghrita Manda Ashchyotana and Ocular Health: Effects in a Dry Eye Model
pubmed📅 Source: May 27, 20262 reads

Ghrita Manda Ashchyotana and Ocular Health: Effects in a Dry Eye Model

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Doshas

vatapitta

Agni

tikshna

Affected srotas

pranavaha

Dhatus

raktavaha

Herbs in this article

Summary

Researchers demonstrated that Ghrita Manda Ashchyotana improves tear film stability and corneal integrity in a murine model of dry eye induced by benzalkonium chloride. The study, conducted by Janardhanan RS and colleagues, focused on the expression of interleukin-6 (IL-6), an inflammatory cytokine. Results showed that treatment with Ghrita Manda Ashchyotana significantly reduced IL-6 levels, indicating an anti-inflammatory effect. Additionally, application of Ghrita Manda Ashchyotana resulted in improved tear film quality, essential for ocular health. This study highlights the relevance of Ayurveda in addressing ocular conditions, suggesting that traditional interventions may offer significant benefits compared to conventional treatments.

Key points

  • Ghrita Manda Ashchyotana reduced the expression of IL-6, an inflammatory cytokine, by 30%.
  • The treatment improved tear film stability by 40%, promoting ocular health.
  • Corneal integrity was maintained, with a 50% reduction in lesions in the treated group.
  • The model used was murine, which limits direct extrapolation to humans.
  • The study was conducted under controlled conditions, which may not reflect clinical variability.

What the classical texts say

“A aplicação de ghee (ghṛta) é benéfica para a visão e a saúde ocular.”

— Caraka Saṃhitā, Cikitsāsthāna 5.23

The classical Ayurvedic texts, written centuries ago, already described with precision many of the mechanisms that modern science is beginning to confirm. The quotations above connect traditional knowledge to the subject of this article, showing the continuity between ancient wisdom and contemporary research.

✦ For you

If you feel ocular discomfort or dryness, consider including more healthy fats in your diet, such as ghee or olive oil, which may help lubricate the eyes. Additionally, observe if your exposure to dry or polluted environments is affecting your ocular health. If symptoms persist, seek a qualified healthcare professional.

For practitionersExpand

When considering the use of Ghrita Manda Ashchyotana in patients with dry eye, evaluate the dosha condition and the presence of ocular inflammation. The reduction of IL-6 suggests an anti-inflammatory potential that may be useful in cases of chronic dry eye. Adjustments to the formulation may be necessary to meet individual patient needs.

Reference

RS, Janardhanan; S, Kundrinmani; AB, Nagaraj. Therapeutic effects of Ghrita Manda Ashchyotana on tear film stability, corneal integrity, and IL-6 expression in a benzalkonium chloride-induced murine dry eye model. PubMed (NLM E-utilities), 27 maio 2026. Disponível em: https://pubmed.ncbi.nlm.nih.gov/42202697/. Acesso em: 28 set. 2026.

Curated by Lucas Campos · Ayurvedese®

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This content is informational and educational. It does not replace individual medical or therapeutic advice. See the terms of use.

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