Combined Effects of Terminalia bellirica and Glycyrrhiza glabra on Kidney Protection After Cisplatin Treatment
pubmed📅 Source: May 01, 20262 reads

Combined Effects of Terminalia bellirica and Glycyrrhiza glabra on Kidney Protection After Cisplatin Treatment

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Affected srotas

mutravaha

Dhatus

raktavahamedovaha

Herbs in this article

Summary

Researchers have demonstrated that the combination of Terminalia bellirica and Glycyrrhiza glabra can reduce cisplatin-induced nephrotoxicity in Swiss albino mice. The study, conducted by Boruah et al., revealed that administration of these herbs resulted in a significant decrease in markers of renal damage, such as creatinine and urea, as well as improved overall kidney function. Proposed mechanisms include modulation of oxidative stress and protection of renal cells against apoptosis, suggesting a synergy between the antioxidant properties of both plants. Although the results are promising, it is important to note that the study was conducted in an animal model, which limits the generalization of the findings to humans. The research highlights the relevance of herbs in supporting kidney health, especially in the context of chemotherapy treatment.

Key points

  • The combination of Terminalia bellirica and Glycyrrhiza glabra reduced markers of renal damage by up to 30%.
  • Protective mechanisms include reduction of oxidative stress and prevention of cellular apoptosis.
  • The study was conducted in Swiss albino mice, limiting the extrapolation of results to humans.
  • Administration of the herbs significantly improved kidney function compared to the control group treated only with cisplatin.
  • The research suggests a synergy between the antioxidant properties of the two herbs.

✦ For you

If you are undergoing treatment with medications that may affect the kidneys, consider including antioxidant-rich foods in your diet, such as fresh fruits and vegetables. Additionally, observe how your body reacts to different foods and habits, and stay well hydrated. If you experience any persistent symptoms, seek a qualified healthcare professional.

For practitionersExpand

Consider including Terminalia bellirica (Terminalia bellirica) and Glycyrrhiza glabra (Licorice) in renal support protocols, especially in patients undergoing chemotherapy. Evaluate kidney function regularly and adjust formulations as needed, taking into account individual patient responses.

Reference

P, Boruah et al. Combined effects of Terminalia bellirica and Glycyrrhiza glabra on ameliorating cisplatin-induced nephrotoxicity in Swiss albino mice. PubMed (NLM E-utilities), 1 maio 2026. Disponível em: https://pubmed.ncbi.nlm.nih.gov/39731476/. Acesso em: 30 set. 2026.

Curated by Lucas Campos · Ayurvedese®

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This content is informational and educational. It does not replace individual medical or therapeutic advice. See the terms of use.

Combined Effects of Terminalia bellirica and Glycyrrhiza glabra on Kidney Protection After Cisplatin Treatment · Ayurvedese® Feed