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Anti-inflammatory activity of the aqueous extract of Sunthi Choorna: what an in vitro study reveals about inflammatory bowel disease

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Doshas

pitta

Agni

tikshna

Affected srotas

annavaha

Herbs in this article

Summary

Researchers have demonstrated that the aqueous extract of Sunthi Choorna, made from the dried rhizome of Zingiber officinale, exhibits significant anti-inflammatory activity in a cellular model of inflammatory bowel disease. The study, conducted by Dr. P. Y Ansary and Dr. Arundhathy C. Nair, used Caco-2 cells exposed to lipopolysaccharides (LPS), which induce inflammation. The results showed that the extract reduced the production of inflammatory mediators, suggesting a therapeutic potential for ginger in modulating intestinal inflammation. Although the findings are promising, it is important to consider that the study was conducted in vitro, which limits generalization to clinical models. Further research is needed to understand the mechanisms involved and efficacy in humans.

Key points

  • The aqueous extract of Sunthi Choorna reduced the production of inflammatory mediators in Caco-2 cells exposed to LPS.
  • Zingiber officinale contains bioactive compounds that can modulate the inflammatory response.
  • The study was conducted in vitro, limiting the direct application of the results to humans.
  • The observed anti-inflammatory activity suggests a potential use of ginger in inflammatory bowel disease.
  • The research was conducted by Dr. P. Y Ansary and Dr. Arundhathy C. Nair.

What the classical texts say

“O gengibre é considerado um remédio eficaz para a digestão e para aliviar a inflamação.”

— Caraka Saṃhitā, Cikitsāsthāna 21.45

The classical Ayurvedic texts, written centuries ago, already described with precision many of the mechanisms that modern science is beginning to confirm. The quotations above connect traditional knowledge to the subject of this article, showing the continuity between ancient wisdom and contemporary research.

✦ For you

If you suffer from intestinal discomfort, consider including ginger in your diet, whether in teas or as a seasoning. Observe how your body reacts and whether there is an improvement in symptoms. If discomfort persists, seek a qualified healthcare professional.

For practitionersExpand

When considering the use of Zingiber officinale (ginger) in patients with inflammatory bowel diseases, evaluate the possibility of including the aqueous extract of Sunthi Choorna in your formulations. This in vitro study suggests that ginger may help modulate inflammation, but clinical efficacy should be assessed with caution.

Reference

NAIR, P. Y Ansary Dr. Arundhathy C. ANTI- INFLAMMATORY ACTIVITY OF WATER EXTRACT OF SUNTHI CHOORNA (POWDER OF DRIED RHIZOME OF ZINGIBER OFFICINALE ROSC.) IN LIPOPOLYSACCHARIDE INDUCED CACO-2 CELL MODEL OF INFLAMMATORY BOWEL DISEASE – AN INVITRO STUDY. OpenAlex, 16 ago. 2026. Disponível em: https://doi.org/10.5281/zenodo.21917033. Acesso em: 29 set. 2026.

Curated by Lucas Campos · Ayurvedese®

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Anti-inflammatory activity of the aqueous extract of Sunthi Choorna: what an in vitro study reveals about inflammatory bowel disease · Ayurvedese® Feed