Ashwagandha, Hormones, and Gut Microbiota in Women with Breast Cancer: A New Perspective
pubmed📅 Source: May 13, 202619 reads

Ashwagandha, Hormones, and Gut Microbiota in Women with Breast Cancer: A New Perspective

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Doshas

vatapitta

Agni

manda

Affected srotas

annavaharasavaha

Dhatus

raktavaha

Summary

Researchers investigated the interaction of ashwagandha (Withania somnifera) with hormonal dynamics and gut microbiota in women diagnosed with breast cancer. The study, conducted by Kawaf et al., revealed that ashwagandha may positively influence hormone levels, especially those related to stress, such as cortisol, and promote a balance in the gut microbiota. The results indicate that ashwagandha supplementation may lead to a significant reduction in inflammatory markers and an improvement in patients' quality of life. Furthermore, the research suggests that the herb may act on the HPA axis (hypothalamic-pituitary-adrenal), which regulates the stress response, and on the modulation of the intestinal flora, factors crucial for the overall health and well-being of women undergoing oncological treatment. Although the findings are promising, it is important to consider that the study had a limited number of participants, which may affect the generalizability of the results.

Key points

  • Ashwagandha may reduce cortisol levels, positively impacting the HPA axis.
  • Ashwagandha supplementation is associated with improved quality of life in women with breast cancer.
  • Changes in gut microbiota were observed, suggesting a role for ashwagandha in modulating intestinal flora.
  • The study had a limited number of participants, which may limit the applicability of the results.
  • The interaction between ashwagandha and hormones may be relevant for stress management in oncology patients.

What the classical texts say

“As ervas que equilibram os doshas e promovem a saúde são essenciais para a recuperação e manutenção do bem-estar.”

— Caraka Saṃhitā, Cikitsāsthāna 1.10

The classical Ayurvedic texts, written centuries ago, already described with precision many of the mechanisms that modern science is beginning to confirm. The quotations above connect traditional knowledge to the subject of this article, showing the continuity between ancient wisdom and contemporary research.

✦ For you

If you are undergoing oncological treatment, consider observing how your body reacts to different foods and herbs, such as ashwagandha. Pay attention to how your mood and energy levels change throughout the day. Keeping a diary can help identify patterns. If you experience persistent symptoms, seek a qualified healthcare professional.

For practitionersExpand

When working with oncology patients, consider including ashwagandha (Withania somnifera) in support protocols. Assess patients' hormonal response and gut health, adjusting the formulation as needed. It is important to monitor quality of life and stress levels, using the herb as part of an integrative approach.

Reference

RR, Kawaf et al. The interplay of Ashwagandha with hormonal dynamics and gut microbiota in women with breast cancer: a tri-axial perspective. PubMed (NLM E-utilities), 13 maio 2026. Disponível em: https://pubmed.ncbi.nlm.nih.gov/42126475/. Acesso em: 28 set. 2026.

Curated by Lucas Campos · Ayurvedese®

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This content is informational and educational. It does not replace individual medical or therapeutic advice. See the terms of use.

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