openalex📅 Source: June 02, 20262 reads

Andrographis paniculata and diabetes control: a review of its compounds and mechanisms of action

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Doshas

pittakapha

Agni

tikshna

Affected srotas

rasavaha

Dhatus

medo

Herbs in this article

Summary

Researchers reviewed the antidiabetic potential of Andrographis paniculata, also known as Kalmegh. The analysis covered phytochemical compounds present in the plant and their pharmacological mechanisms. The authors, Deepti Ghai and Anupma Mehrotra, highlighted that Andrographis may act to reduce blood glucose levels, possibly through modulation of insulin secretion and improvement of insulin sensitivity. Additionally, the plant demonstrated antioxidant properties that may protect pancreatic beta cells, responsible for insulin production. Although the results are promising, the review also points out limitations, such as the need for more clinical studies in humans to validate these findings and better understand effective and safe dosages. The connection between Ayurvedic principles and the effects of Andrographis on blood sugar control is an area that deserves more attention, especially considering the traditional use of the plant to treat metabolism-related conditions.

Key points

  • Andrographis paniculata may reduce blood glucose levels through modulation of insulin secretion.
  • The plant's antioxidant compounds protect pancreatic beta cells, improving insulin function.
  • The review highlights the need for more clinical studies to validate the antidiabetic effects in humans.

✦ For you

If you are looking for ways to support blood sugar control, consider including Andrographis paniculata in your routine. Observe how your body reacts to this herb and keep a food diary to identify patterns. Remember that it is important to consult a qualified healthcare professional if symptoms persist.

For practitionersExpand

In clinical practice, Andrographis paniculata (Kalmegh) can be considered as an option for patients with diabetes, especially those seeking integrative approaches. Assess Agni function and beta cell condition when formulating a treatment. It is essential to monitor patient response and adjust dosage as needed, always taking into account available evidence.

Reference

GHAI, Deepti; MEHROTRA, Anupma. Anti-diabetic Potential of Andrographis Paniculata (Kalmegh): A Comprehensive Review of Phytochemical Constituents and Pharmacological Mechanisms. OpenAlex, 2 jun. 2026. Disponível em: https://doi.org/10.25258/ijddt.16.43s.133. Acesso em: 28 set. 2026.

Curated by Lucas Campos · Ayurvedese®

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This content is informational and educational. It does not replace individual medical or therapeutic advice. See the terms of use.

Andrographis paniculata and diabetes control: a review of its compounds and mechanisms of action · Ayurvedese® Feed